The novel is a unique and satirical work, narrated by a dead man, Bras Cubas, who recounts his life from beyond the grave. The story is filled with ironic humor and philosophical musings as Bras Cubas explores his past, his relationships, and the societal norms of his time. The narrative breaks conventional storytelling norms, often addressing the reader directly and jumping through time without warning. Themes of love, wealth, power, and the human condition are explored, providing a critique of 19th-century Brazilian society.

The novel is a semi-autobiographical tale of a young man in Peru who falls in love with his divorced aunt, Julia, while working at a radio station. Their scandalous romance unfolds amidst the backdrop of a chaotic radio station run by a brilliant but unstable Bolivian scriptwriter who churns out daily soap operas. The narrative alternates between the protagonist's real life and the melodramatic world created by the scriptwriter, blending reality and fiction in a humorous and poignant exploration of love and creativity.

"Cronopios and Famas" is a whimsical collection of short stories and vignettes that defy traditional narrative structures, blending elements of surrealism, fantasy, and humor. The book is divided into several sections, each exploring different themes and concepts through the interactions of its titular characters: the Cronopios, idealistic and imaginative beings; the Famas, pragmatic and organized; and the Esperanzas, who are indifferent and conformist. Through these characters, the work delves into the absurdities of daily life, human behavior, and the struggle between chaos and order, presenting a unique and playful exploration of the human condition.