The book is a heartwarming story of a young orphan boy of mixed ancestry who is raised by his Cherokee grandparents in the Appalachian Mountains during the Great Depression. His grandparents teach him the Cherokee way of life, including their spiritual beliefs, love for nature, respect for all living things, and the importance of tolerance and understanding. Despite the hardship and prejudice they face, they impart wisdom, love, and a unique perspective on life to the young boy.