The novel explores the life of Malachi Constant, the richest man in a future America, who has gained his wealth due to his father's foresight in investing in companies that benefit from the space race. The narrative takes him from Earth to Mars, Mercury, back to Earth, and finally to one of Saturn's moons, Titan. Along the way, he experiences a series of bizarre, humorous, and tragic events that reveal the senselessness of war and the emptiness of a life devoid of love. The novel offers a biting critique of capitalism, militarism, and religion, while also exploring themes of free will, determinism, and the search for meaning.

"The Glass Bees" is a novel set in a future dystopian society, where technology has advanced to the point where robotic bees are being used for honey production. The story follows a former cavalryman who, desperate for employment, accepts a job from a powerful technocrat to test out these mechanical bees. As the protagonist gets more involved in the technocrat's world, he begins to question the morality and implications of such advancements, leading to a deep exploration of the intersection between technology and nature, and the potential consequences of unchecked technological progress.

The novel follows a mentally unstable man who begins to experience visions after being hit by a mysterious pink light. Convinced the light is a divine entity named VALIS, he and his friends embark on a quest to understand and communicate with it. As they delve into philosophy, religion, and science, the boundaries between reality and delusion begin to blur, leaving both the characters and the reader questioning the nature of existence.