The novel centers around an aging businessman who, upon hearing nightly sounds from the nearby mountain, begins to confront his own mortality and the complexities within his family. As he navigates his strained relationship with his wife, his adulterous son, and his daughter-in-law whom he harbors feelings for, he experiences a profound sense of solitude and existential dread. The narrative subtly explores themes of aging, alienation, and the ephemeral nature of life.

The novel tells the story of a young Irish woman, Eilis Lacey, in the 1950s who, unable to find work at home, is sent to Brooklyn by a helpful priest where she builds a new life. She finds work, studies to become a bookkeeper, and falls in love with an Italian plumber named Tony. However, a family tragedy forces her to return to Ireland, where she must choose between her new life in America and her old life at home.

"Fates and Furies" is a novel split into two parts, providing two perspectives on a single marriage. The first half of the book, "Fates," is told from the point of view of the husband, Lotto, a charismatic but failed actor turned successful playwright, who views his marriage as happy and his wife as supportive. The second half, "Furies," is told from the perspective of his wife, Mathilde, revealing her hidden past and the sacrifices and manipulations she has performed to maintain their life together. The novel explores themes of love, secrets, and the different narratives created within a relationship.

This novel follows the lives of three friends in their thirties living in New York City in the months leading up to and following the September 11 attacks. All children of privilege, they struggle with their careers, love lives, and identities against the backdrop of a changing world. The narrative explores themes of entitlement, disillusionment, and the often complicated nature of adult friendships.