The novel revolves around the lives of the Lambert family, an old-fashioned midwestern couple and their three adult children. The parents, Alfred and Enid, are dealing with Alfred's Parkinson's disease and their own marital problems, while their children are each facing their own personal and professional crises. The narrative explores the themes of family dynamics, societal expectations, and the struggles of modern life. The story climaxes with the family's last Christmas together at their childhood home.

Set in the 1980s during the era of Margaret Thatcher's conservative government in Britain, this novel follows the life of a young gay man named Nick Guest. Coming from a middle-class background, he moves into the home of his wealthy friend's family and becomes infatuated with the opulence and power of the upper class. As he navigates his way through this new world, he also explores his sexuality, all while dealing with the societal and political implications of the AIDS crisis.

This novel is a gritty, raw portrayal of a group of heroin addicts living in Edinburgh, Scotland. The narrative is non-linear and told from multiple perspectives, providing a deep dive into the minds and lives of these characters. The story explores themes of poverty, addiction, friendship, and the struggle to escape one's circumstances, all set against the backdrop of a bleak urban landscape. It is known for its strong Scottish dialect, graphic content, and dark humor.

"Never Mind" is a darkly humorous and deeply disturbing narrative about an aristocratic English family. The story primarily focuses on a five-year-old boy who is the victim of his sadistic and sexually abusive father, while his mother, an alcoholic, ignores the situation. The narrative also provides a scathing critique of the British upper class through its exploration of the family's decadent lifestyle and morally corrupt behavior.

"Some Hope" is a darkly humorous novel that delves into the life of a man who struggles to overcome his traumatic past and drug addiction. He is invited to a lavish party filled with Britain's aristocracy, where he must confront his past and deal with the pretentious and shallow society he is part of. The narrative explores themes of abuse, recovery, and the struggle to find redemption and hope amidst despair.

The novel follows the life of Patrick Melrose, a man battling with his drug addiction and his troubled relationship with his parents. Patrick tries to come to terms with his mother’s decision to leave her estate to a New Age foundation rather than to him, her only son. The story delves into the complexities of inheritance, parenthood, and the lasting impact of childhood trauma. The narrative shifts between the perspectives of Patrick, his wife, and their two young sons, providing a multi-dimensional view of the family's struggles.

The novel follows a young American poet on a prestigious fellowship in Madrid, Spain, where he grapples with his work, relationships, and sense of self. He struggles with his own perceptions of authenticity, both in his poetry and his personal life, while navigating the cultural and language barriers of a foreign country. The protagonist's experiences are marked by a constant tension between reality and artifice, as he questions the value and impact of his own art in the face of world events.