The novel centers around Moses Herzog, a middle-aged, intelligent yet distressed man who is going through a mid-life crisis. After his second marriage fails, he falls into a state of emotional turmoil and begins writing letters to friends, family, and even famous figures, expressing his philosophical thoughts and personal feelings. His journey of self-discovery and understanding forms the crux of the story. It's a profound exploration of a man's struggle with the complexities of life and his quest for meaning.

Set in a bleak New England landscape, the book tells the story of Ethan Frome, a poor, hardworking farmer who is married to a sickly, bitter woman named Zeena. When Zeena's young cousin Mattie comes to live with them, Ethan becomes infatuated with her, leading to a tragic love triangle. The narrative explores themes of passion, duty, and the oppressive nature of rural poverty.

The novel is a final look into the life of Harry "Rabbit" Angstrom, a former high-school basketball star, now in his mid-fifties, overweight and grappling with several health issues. Despite his success in business, his personal life is in shambles, with his wife addicted to alcohol and his son to drugs. Harry, struggling with his mortality, is trying to understand his past and make sense of his future, while dealing with the changing American society and the consequences of his own choices.

This novel revolves around the cursed Pyncheon family, who live in a gloomy New England mansion, cursed due to the actions of their ancestor who had an innocent man hanged as a witch to seize his property. The story explores themes of guilt, retribution, and atonement, and the narrative is interspersed with the author's philosophical musings. The present-day Pyncheons include an old maid, a daguerreotypist, and their elderly, reclusive cousin who returns to the house after a mysterious absence of many years.

The Human Stain is a novel that explores the life of Coleman Silk, a classics professor in a small New England town who is forced to retire after accusations of racism. The story delves into Silk's personal history, revealing that he is a light-skinned African American who has been passing as a Jewish man for most of his adult life. His affair with a much younger, illiterate janitor further scandalizes the community. The novel examines themes of identity, race, and the destructive power of public shaming.

This novel is a contemporary, multicultural exploration of family life, love, and identity. It follows the lives of two mixed-race families, the Belseys and the Kipps, who are linked by their shared professions in academia and a complex web of marital and extramarital relationships. The story is set against the backdrop of Wellington, a fictional New England town, and explores themes of race, class, and cultural clash. It also delves into the world of academia, examining the politics and conflicts that arise in that environment.

"Home Fire" is a contemporary reimagining of Sophocles' Antigone set against the backdrop of modern-day London and Syria. The novel explores the lives of five characters caught in a complex web of love, loyalty, and sacrifice. The story revolves around two British-Pakistani families, each struggling with their own dilemmas related to identity, radicalism, and loyalty. One family is headed by a powerful politician who disowns his jihadist son, while the other consists of three orphaned siblings whose lives are turned upside down when their brother is accused of joining ISIS. The novel explores the consequences of their actions, questioning the extent to which one can go for love and loyalty.

In "Boy, Snow, Bird," a young woman named Boy Novak escapes her abusive father in New York City to settle in a small town in Massachusetts, where she marries a widower and becomes stepmother to his daughter, Snow. After giving birth to her own daughter, Bird, who is dark-skinned, it is revealed that her husband and stepdaughter are light-skinned African Americans passing as white. The book explores themes of identity, beauty, and the damaging effects of racism as Boy grapples with her feelings towards Snow and Bird, and the societal implications of their different skin tones.

The novel delves into the lives of a family grappling with the impact of mental illness across generations. It explores the bonds and strains among family members as they confront the challenges posed by the eldest son's severe anxiety and depression. Through shifting perspectives, the narrative examines the ways in which each family member copes with their shared and individual struggles, illuminating the profound effects of love, loyalty, and the legacy of mental health issues on their relationships and choices. The story is a poignant and insightful portrayal of the complexities of familial love and the enduring human capacity for resilience in the face of emotional turmoil.