The novel follows the lives of two boys growing up in Brooklyn, New York in the 1970s. Despite their racial differences, one being white and the other black, they form a deep friendship bonded by their shared interest in comic books, music and a magical ring that grants them superpowers. As they grow older, their paths diverge due to their racial and societal differences, with one becoming a successful music journalist and the other succumbing to a life of crime. The book is a profound exploration of race, identity, friendship and the impact of gentrification.

The book centers on Asher Lev, a young boy from a Hasidic Jewish family in Brooklyn, who possesses a prodigious artistic talent that conflicts with his deeply religious community and his relationship with his parents. As Asher grows, he must navigate the tension between his passion for painting and the expectations of his faith and family. His journey of self-discovery and struggle for artistic expression leads him to study under a renowned artist, which further alienates him from his community and leads to a profound personal and spiritual reckoning. The novel explores themes of identity, tradition, and the often-painful pursuit of individuality within the confines of a strict cultural milieu.

This novel explores the life of a young Barbadian-American girl growing up in Brooklyn during the Great Depression and World War II. The protagonist struggles with her identity as she navigates the cultural divide between her parents' traditional Barbadian values and her own American aspirations. The story delves into the themes of immigration, cultural identity, race, and gender, as the protagonist comes of age and seeks to establish her independence.

The novel tells the story of a young Irish woman, Eilis Lacey, in the 1950s who, unable to find work at home, is sent to Brooklyn by a helpful priest where she builds a new life. She finds work, studies to become a bookkeeper, and falls in love with an Italian plumber named Tony. However, a family tragedy forces her to return to Ireland, where she must choose between her new life in America and her old life at home.

This novel tells the story of Winter Santiaga, the teenage daughter of a powerful drug lord in Brooklyn. After her father's empire collapses and he is imprisoned, Winter's privileged lifestyle ends abruptly, and she must navigate the harsh realities of poverty, addiction, and the criminal justice system. The narrative explores themes of race, class, and the consequences of choices, offering a gritty, unflinching look at life in urban America.

The novel is a poignant exploration of friendship, memory, and loss, set against the backdrop of 1970s Brooklyn. It follows the coming-of-age story of August, an African American girl who, along with her friends Sylvia, Angela, and Gigi, navigates the complexities of adolescence, the harsh realities of their neighborhood, and the unyielding bonds of friendship. As August looks back on her youth from her adult years, the narrative weaves a tapestry of her past experiences, capturing the joy, vulnerability, and resilience of young black girls growing up in a world that often fails to protect them.

"Red at the Bone" is a multi-generational novel that explores the lasting impact of past decisions on the present and future. The story begins at a 16-year-old girl's coming-of-age ceremony in Brooklyn and then delves into the past, revealing the complex histories of her parents and grandparents. The narrative is a powerful exploration of identity, ambition, love, and the ways in which history and personal circumstances can shape a family's life.