The novel follows the story of a young woman who wins a guest editorship at a magazine in New York City and, after a series of personal and professional disappointments, suffers a mental breakdown and returns to her family, where she continues to struggle with depression and suicidal thoughts. The protagonist's experiences in psychiatric institutions and her attempts to reclaim her life are depicted with brutal honesty, making it a poignant exploration of mental illness and the societal pressures faced by women in the mid-20th century.

Set against the backdrop of the Prague Spring period of Czechoslovak history, the novel explores the philosophical concept of Nietzsche's eternal return through the intertwined lives of four characters: a womanizing surgeon, his intellectual wife, his naïve mistress, and her stoic lover. The narrative delves into their personal struggles with lightness and heaviness, freedom and fate, love and betrayal, and the complexities of human relationships, all while offering a profound meditation on the nature of existence and the paradoxes of life.

The novel revolves around the lives of the Lambert family, an old-fashioned midwestern couple and their three adult children. The parents, Alfred and Enid, are dealing with Alfred's Parkinson's disease and their own marital problems, while their children are each facing their own personal and professional crises. The narrative explores the themes of family dynamics, societal expectations, and the struggles of modern life. The story climaxes with the family's last Christmas together at their childhood home.

The novel follows the life of a travel writer, who, after the death of his son and subsequent separation from his wife, embarks on a journey of self-discovery. He meets an eccentric dog trainer who is the complete opposite of his introverted and orderly self. Through their relationship, he learns to embrace the unpredictability of life and move beyond his grief. The story is a poignant exploration of love, loss, and the unexpected turns life can take.

"A Pale View of Hills" is a novel about a Japanese woman named Etsuko, who, after the suicide of her eldest daughter, reflects on her past in post-war Nagasaki. She recalls her friendship with Sachiko, a woman who plans to escape her miserable life by moving to America with her daughter Mariko. The narrative subtly explores themes of memory, guilt, and cultural dislocation while unveiling the complexities of human relationships and the haunting effects of the past on the present.

"Bad News" is the second novel in a series that follows the life of Patrick Melrose, a man from a wealthy but deeply troubled family. In this installment, Patrick, now 22, must travel to New York to collect his father's ashes. As he navigates the city, he struggles with his addiction to drugs and alcohol, and grapples with the traumatic memories of his abusive father. The narrative provides a darkly comic and deeply poignant exploration of addiction, trauma, and the struggle for redemption.

A high school freshman becomes a social outcast after calling the police to break up a summer party and refuses to explain why. As she navigates the challenges of high school, she struggles with a traumatic event from the party that has left her feeling silenced. Throughout the year, she slowly regains her voice and confronts her attacker, ultimately revealing the truth about what happened that night.

This novel explores the idea of alternate realities through the story of two brothers, one a successful dentist and the other a famous writer. The narrative is divided into five parts, each presenting a different version of their lives. As the story progresses, the characters grapple with issues of identity, mortality, and the complex relationship between art and life. The novel is a profound examination of the choices we make and the different paths our lives could take as a result.

"The Laws" is a philosophical novel that follows the life of a young woman studying philosophy who becomes intrigued by the concept of laws, both societal and personal. Over the course of seven years, she engages in relationships with seven different men, each representing a different aspect of her studies including a priest, a physicist, an artist, a psychiatrist, a lawyer, a biologist, and a writer. Each relationship provides a new perspective on her quest to understand the laws of the universe and human nature.

"The Love of a Good Woman" is a collection of eight short stories, each delving into the complex nature of relationships, particularly focusing on women. The narratives explore various themes such as love, betrayal, death, and the often overlooked intricacies of everyday life. Set in small-town Canada, the stories are filled with characters grappling with their desires, secrets, and the unexpected turns of life, offering a profound and nuanced exploration of human behavior and emotions.

All My Puny Sorrows is a poignant exploration of the complex relationship between two sisters, one a successful concert pianist battling severe depression and the other a struggling writer trying to support her. The narrative delves into themes of mental illness, suicide, love, and the power of familial bonds. It grapples with the moral and ethical questions surrounding assisted suicide, the struggle to understand a loved one's pain, and the lengths to which one might go to help them find peace.

"Everything I Never Told You" is a gripping and emotionally charged novel that delves into the complexities of a Chinese-American family living in 1970s Ohio. When their daughter Lydia goes missing and is later found dead, the Lee family is shattered by grief and forced to confront their own secrets and insecurities. As they navigate through their individual struggles, the novel explores themes of identity, race, and the pressures of societal expectations, painting a poignant portrait of a family on the brink of collapse.

"Ducks, Newburyport" is a sprawling and ambitious novel that explores the inner thoughts and experiences of an Ohio housewife as she goes about her daily life. The narrative is presented in a stream-of-consciousness style, with the protagonist's mind constantly jumping between various topics, memories, and anxieties. Through her musings, the novel delves into themes of motherhood, love, politics, and the anxieties of modern society, offering a unique and intimate portrait of one woman's existence.