Set in a psychiatric hospital in Oregon, the novel is narrated by a half-Native American patient known as Chief Bromden, who pretends to be deaf and mute. The story follows the arrival of a new patient, a boisterous, rebellious man who challenges the oppressive and dehumanizing system of the hospital, particularly the tyrannical Nurse Ratched. The book explores themes of individuality, rebellion, and the misuse of power, ultimately leading to a tragic conclusion.

Set in 1920s Berlin, the book follows the life of Franz Biberkopf, a man recently released from prison who is trying to make an honest life for himself. However, he is drawn back into the criminal underworld due to circumstances and the influence of his acquaintance, Reinhold. The book is a vivid portrayal of city life in Weimar-era Germany, exploring themes of poverty, crime, redemption and the struggle to maintain one's morality amidst chaos and corruption.

The novel is a disturbing and graphic exploration of the mind of a wealthy, young and handsome Wall Street investment banker who is also a psychopathic serial killer. He leads a double life, appearing to be a charming and sophisticated businessman by day, while indulging in horrific acts of violence and murder by night. The narrative provides a satirical critique of 1980s American consumer culture, vanity, and excess, while also delving into the dark underbelly of human nature.

"Requiem for a Dream" is a harrowing tale that explores the depths of addiction and its devastating consequences. The narrative follows the lives of four characters, each battling their own form of substance abuse. The main character, a woman in her old age, becomes addicted to diet pills in her quest to lose weight and appear on a television game show, while her son, his girlfriend, and his best friend are all caught up in heroin addiction. As their dependencies deepen, their lives spiral out of control, leading to tragic endings. The book serves as a stark and brutal depiction of drug addiction and its destructive effects on individuals and their relationships.