The novel is a sprawling epic that spans the period from the 1893 World's Fair to the years following World War I. It follows the stories of several characters including the anarchist Traverse family, a group of balloonists, a detective, and a mathematician. The book explores themes of anarchism, capitalism, and technology, and incorporates elements of science fiction, adventure, and historical fiction. It is noted for its complex structure and dense, multifaceted narrative.

The book is an alternate history novel that explores a world in which the Black Death plague of the 14th century was far more lethal to Europeans, nearly wiping them out. As a result, world history is dramatically reshaped: Islamic and Buddhist societies emerge as the dominant global powers, leading to vastly different technological, cultural, and social developments. The narrative spans several centuries, following a group of characters who are reincarnated into various lives and roles, allowing the reader to experience the evolution of this alternate world through their interconnected stories. The novel delves into themes of history, religion, technology, and human nature, all while imagining a world both familiar and strange, shaped by different forces and ideas than those that have shaped our own history.

The Baroque Cycle is an expansive historical fiction series that weaves together a rich tapestry of themes including science, politics, philosophy, and adventure during the late 17th and early 18th centuries. The narrative follows an eclectic cast of characters, ranging from natural philosophers and mathematicians to pirates and nobles, as they navigate the complex socio-political transformations of the Enlightenment era. The series delves into the origins of modern finance, the scientific revolution, and the geopolitical power shifts of the time, all while exploring the intricate interplay between the emerging modern world and the intricate, ornate culture of the Baroque period.