Set in 19th century China, the novel centers around the lifelong friendship of Lily and Snow Flower. Despite their different social classes, the two communicate through a secret language known as "nu shu" written on a fan. The story explores the rigid societal norms of the time, particularly the practice of foot binding and arranged marriages. As they navigate through the hardships of their lives, their friendship is tested, leading to a devastating betrayal that impacts their relationship.

This novel presents a unique narrative structure, unfolding through a series of first chapters of an autobiography that its protagonist, a Lebanese woman named Sarah, attempts to write multiple times but never completes. Through these fragmented beginnings, readers explore Sarah's complex life, from her upbringing in a tumultuous Beirut to her experiences as an immigrant in the United States, facing the challenges of identity, belonging, and self-expression. The book offers a rich tapestry of family dynamics, cultural clashes, and personal reinvention, all while showcasing the struggles of articulating one's life story amidst the chaos of historical and personal upheavals.