This novel weaves together the lives of diverse characters through a narrative that spans decades, centering on a teenage runaway with psychic abilities. As she becomes embroiled in a covert war between immortal factions, the story explores themes of mortality, power, and the interconnectedness of human lives. The intricate plot moves through different times and places, revealing a hidden world of mysticism and a looming apocalyptic crisis, all while examining the impact of our actions on the future of the planet.

Ghostwritten is a complex, interconnected narrative that spans the globe, featuring nine different characters in nine different locations, including a cult member in Okinawa, a jazz buff in Tokyo, a British investment banker in Hong Kong, an old woman running a tea shack in China, a transmigrating spirit in Mongolia, a ghostwriter in London, a physicist in Ireland, a late-night radio DJ in New York, and a noncorporeal entity in a global network. Each story is seemingly separate, but as the novel progresses, the connections between them become more apparent, creating a web of incidents and interactions that span space and time.

The novel centers on a young Indian computer programmer whose dreams of a new life in the United States are derailed by a series of unfortunate events. Desperate to avoid deportation after losing his job, he unleashes a mischievous computer virus in a bid to regain his employer's attention, but the plan spirals out of control. The virus rapidly spreads across the globe, causing widespread chaos and inadvertently linking the fates of an eclectic mix of characters, from Bollywood actresses to ambitious Silicon Valley entrepreneurs. The story is a satirical exploration of the complexities of globalization, the illusions of the American dream, and the unpredictable ways in which technology can disrupt the world.