The novel revolves around a man who becomes sexually aroused by staging and participating in real car-crashes, a fetish that spirals further out of control when he meets a like-minded woman. It explores the disturbing intersection of technology, sexuality, and violence, pushing the boundaries of social norms and challenging the reader's perception of reality.

The novel is a phantasmagorical journey through a world where reality is under siege by the diabolical machinations of a mad scientist who has unleashed desire machines that warp perception and desire. The protagonist, Desiderio, an employee of the Ministry of Determination, embarks on a quest to stop Doctor Hoffman, confronting a series of bizarre and surreal challenges that blend eroticism, philosophy, and violence. As Desiderio travels through cities and landscapes transformed by the machines, he encounters a cast of eccentric characters and experiences dreamlike adventures that challenge the boundaries of reality, identity, and sanity, culminating in a confrontation with the enigmatic Doctor and the resolution of his own complex relationship with Hoffman's daughter.

In this novel, a man crashes a stolen aircraft into the Thames River near a quiet London suburb, only to emerge unscathed and with the newfound ability to transform reality. As he begins to exert a strange and seductive influence over the town's inhabitants, the boundaries between the mundane and the fantastic blur. The protagonist's powers grow, leading to a surreal and psychedelic transformation of the town, its people, and himself. The narrative explores themes of liberation, sexuality, and the human psyche, presenting a hallucinatory vision of human potential and the limitless expanses of the imagination.