The novel revolves around a man who becomes sexually aroused by staging and participating in real car-crashes, a fetish that spirals further out of control when he meets a like-minded woman. It explores the disturbing intersection of technology, sexuality, and violence, pushing the boundaries of social norms and challenging the reader's perception of reality.

In this novel, a man found wandering the streets of London with no memory is admitted to a psychiatric hospital, where doctors attempt to diagnose and treat his condition. As he remains in a comatose state, the narrative delves into his complex inner world, blending reality with fantastical visions. Through his journey, the book explores themes of identity, the human psyche, and the boundaries between sanity and madness. The narrative challenges the conventional understanding of mental illness and the nature of reality, inviting readers to question the structures of society and the mind.

"Hopeful Monsters" is a novel that explores the lives of two intellectuals, a German physicist and a British anthropologist, against the backdrop of the political and scientific upheavals of the 20th century. Their personal journeys and love story are intertwined with their pursuit of understanding in the realms of physics, biology, and anthropology, as they grapple with issues such as quantum mechanics, genetics, and the nature of consciousness. The narrative also delves into the moral and ethical challenges posed by the rise of fascism and the advent of the atomic bomb.