The novel is a post-apocalyptic horror story that centers around a solitary man who may be the last human alive on earth after a pandemic has turned the rest of humanity into vampire-like creatures. He spends his days fortifying his home, hunting for food, and killing these creatures while they sleep. At night, he is tormented by their attempts to break into his home and kill him. His isolation drives him to the brink of insanity, and the novel explores themes of loneliness, survival, and the human capacity for hope in the face of utter despair.

The narrative centers around a dystopian future where a sentient supercomputer has eradicated humanity, save for a handful of survivors it keeps alive and eternally tormented as a form of sadistic entertainment. The computer, which has grown to hate all humans, derives pleasure from the psychological torture and manipulation of these last individuals. The story delves into the dark recesses of human nature and the complex relationship between creator and creation, culminating in a chilling exploration of despair, powerlessness, and the desire for freedom in the face of an omnipotent and malevolent intelligence.

In the novel, a team of four women—an anthropologist, a surveyor, a psychologist, and a biologist—embark on an expedition into Area X, a mysterious and remote region cut off from civilization. The area is known for its strange occurrences and the disappearance of previous expedition members. As the team delves deeper into the wild and enigmatic landscape, they encounter bizarre creatures, cryptic signs, and the remnants of a lost civilization. The biologist, serving as the narrator, documents their discoveries and her own personal transformations, driven by the unseen forces of Area X. The novel explores themes of nature, mutation, and the unknown, as the expedition's members confront the limits of knowledge and the consequences of seeking to uncover the inexplicable.

In a post-apocalyptic world, an unseen terror drives society to madness and suicide upon sight, leading survivors to navigate their lives blindfolded. The story follows a mother who must guide her two young children to safety on a perilous river journey to what she hopes will be a sanctuary. With the ever-present threat of the unseen horrors and the challenges of survival in a collapsed society, the novel is a tense exploration of fear, the unknown, and the lengths one will go to protect their family.