The novel follows the life of Daisy Goodwill Flett, a seemingly ordinary woman, from her birth in Canada in 1905 to her death. It explores her experiences as a mother, wife, and widow, as well as her work as a gardener and her later years as a columnist. The book is unique in that it is written in a variety of styles including letters, diary entries, and third-person narrative, and it explores themes of identity, love, and the often overlooked lives of women.

The novel is a poignant tale of Ruth, a young woman from a small town in Illinois, who endures a life marked by hardship and disappointment. Raised by a neglectful mother and overshadowed by her brother's tragic death, Ruth seeks solace in her marriage to a man who turns out to be abusive. Despite the bleakness of her circumstances, she finds strength in her love for reading and the bond with her kind-hearted mother-in-law. The narrative, rich with themes of resilience, the complexity of family relationships, and the search for self-worth, unfolds through Ruth's perspective as she navigates the challenges of her life, ultimately striving for a sense of hope and redemption.

"Anything is Possible" is a collection of interconnected stories exploring the lives and struggles of various residents in a small town in Illinois. The stories delve into the characters' pasts, revealing their secrets, regrets, and the complexities of their relationships. The book explores themes of poverty, trauma, and the human capacity for change, demonstrating that despite hardships and heartbreak, anything is possible.