The novel explores the life of two sisters, Ruth and Lucille, who are raised by a series of relatives in a small, secluded town in Idaho after their mother's suicide. The girls' lives are profoundly affected by the eccentric and transient lifestyle of their aunt Sylvie, who becomes their guardian. The narrative delves deeply into themes of family, identity, womanhood, and the impermanence of life, ultimately leading to a divide between the sisters as they choose different paths in life.

The book is a tale of two childhood friends, one of whom believes he is God's instrument. The story is set in a New England town during the 1950s and 1960s and follows the lives of the two boys, one small and with a strange voice, who has visions of his own death and believes he is an instrument of God, and the other, the narrator, who struggles with faith. The novel explores themes of faith, fate, and the power of friendship against a backdrop of historical and political events, including the Vietnam War.

This novel explores the complex relationships between four Chinese-American mothers and their American-born daughters. The narrative switches between the perspectives of the eight women, revealing their pasts, their struggles with cultural identity, and the misunderstandings that have grown between the generations. The mothers, who all experienced hardship in their native China, want their daughters to have better lives and thus push them to excel in America. The daughters, in turn, struggle to reconcile their American surroundings with their Chinese heritage.

"Dinner at the Homesick Restaurant" is a novel about the life of the Tull family, which is marked by abandonment and discord, but also love and resilience. The story is told from the perspective of each family member, providing a unique viewpoint on the family's dynamics and history. The matriarch, Pearl, struggles to raise her three children, Cody, Ezra, and Jenny, after their father abandons them. Each child deals with the abandonment and their dysfunctional family in different ways, shaping their adult lives. The novel explores themes of family, love, abandonment, and the idea of home.

"Demon Copperhead" is a short story by Barbara Kingsolver about a young woman named Codi who returns to her small hometown in Arizona to care for her father, who is dying of Alzheimer's disease. As she reconnects with her past and the people in her community, Codi discovers a dark secret about her family's history and must come to terms with the truth. The story explores themes of family, identity, and the impact of the past on the present.

All My Puny Sorrows is a poignant exploration of the complex relationship between two sisters, one a successful concert pianist battling severe depression and the other a struggling writer trying to support her. The narrative delves into themes of mental illness, suicide, love, and the power of familial bonds. It grapples with the moral and ethical questions surrounding assisted suicide, the struggle to understand a loved one's pain, and the lengths to which one might go to help them find peace.