This novel is a satirical critique of small-town life, following the story of a young, ambitious woman who moves from the city to a quiet, conservative town in the Midwest with her new husband. Despite her attempts to bring culture and progress to the town, she is met with resistance and ostracism from the closed-minded locals. The protagonist's struggle against traditional norms and her ultimate disillusionment highlight the stifling conformity and lack of intellectual stimulation in rural America.

"The Book of Daniel" is a semi-fictional novel that explores the lives of the Isaacson family, specifically focusing on the children, Daniel and Susan, after their parents, accused of being Communists, are executed. The narrative is a combination of historical fiction and a political commentary, providing a deep exploration of the Red Scare in the United States during the Cold War era. The novel is a critical examination of social, political, and familial dynamics in a time of national fear and paranoia.

This novel tells the story of Dr. Wilbur Larch—saint and obstetrician, founder and director of the orphanage in the town of St. Cloud's, Maine, and a man of rare compassion and an addiction to ether. Dr. Larch loves all his orphans, especially Homer Wells, who is never adopted and becomes his invaluable apprentice. As Homer comes of age, he must leave the only home he's ever known to explore the world outside, a world filled with temptations and moral dilemmas, from the struggle over abortion to the question of what constitutes a family.

The novel follows the life of a bright and dedicated young man, Martin Arrowsmith, who dreams of making significant contributions to medical science. He faces a constant struggle between his ambition and the demands of his professional and personal life. His journey takes him from a small Midwestern town to the prestigious universities of the East Coast, and eventually to a deadly outbreak in the Caribbean. Throughout his journey, he grapples with the corruption, greed, and mediocrity that he finds pervading the medical field, all while trying to remain true to his scientific ideals.