"The Stress of Her Regard" by Tim Powers is a supernatural thriller that follows the life of a young doctor, Michael Crawford, who becomes entangled with a group of poets haunted by a mysterious force that feeds off their creativity. As Michael delves deeper into the lives of these poets, he discovers that they are all connected by a common thread: they have all been visited by a seductive, vampiric creature known as a Lamia. As he struggles to uncover the truth behind the Lamia's power and its connection to the poets, Michael must confront his own demons and fight for his own survival.

This novel weaves together the lives of diverse characters through a narrative that spans decades, centering on a teenage runaway with psychic abilities. As she becomes embroiled in a covert war between immortal factions, the story explores themes of mortality, power, and the interconnectedness of human lives. The intricate plot moves through different times and places, revealing a hidden world of mysticism and a looming apocalyptic crisis, all while examining the impact of our actions on the future of the planet.