The play is a poignant exploration of the life of a brilliant and exacting English professor who is diagnosed with terminal ovarian cancer. As she undergoes aggressive and painful treatment, she reflects on her life and work, particularly her study of the metaphysical poets, with a focus on the intricacies of John Donne's Holy Sonnets. The narrative juxtaposes the complexities of human emotions with the clinical detachment of the medical profession, ultimately offering a meditation on mortality, the value of human connection, and the meaning of life when faced with the imminence of death. Through her illness, the protagonist confronts the irony and tragedy of her situation, using her wit to cope with her deteriorating condition and to question the significance of her scholarly achievements.

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