The novel follows the life of Patrick Melrose, a man battling with his drug addiction and his troubled relationship with his parents. Patrick tries to come to terms with his mother’s decision to leave her estate to a New Age foundation rather than to him, her only son. The story delves into the complexities of inheritance, parenthood, and the lasting impact of childhood trauma. The narrative shifts between the perspectives of Patrick, his wife, and their two young sons, providing a multi-dimensional view of the family's struggles.

"The Neapolitan Novels" is a four-part series that explores the intricate and lifelong friendship between two women from Naples, Italy. The series spans several decades, beginning in the 1950s, and provides a detailed examination of the women's lives, struggles, and the societal pressures they face. The narrative delves into themes of identity, friendship, love, violence, and socio-political changes in post-war Italy. The series is known for its rich character development and vivid portrayal of female friendship.

"Dept. of Speculation" follows the story of a woman navigating her life as a writer, a wife, and a mother. The novel explores her journey through marriage, motherhood, and the struggles of maintaining her own identity amidst these roles. It also delves into the hardships of dealing with infidelity and the complexities of love and relationships. The narrative is presented in fragmented pieces, reflecting the protagonist's scattered thoughts and emotions.

This novel tells the story of a Bangladeshi woman named Nazneen who moves to London at the age of 18 for an arranged marriage to a man 20 years her senior. The narrative explores her life in the city, her struggles with her unhappy marriage, her affair with a young radical, and her attempts to reconcile her traditional upbringing with her new surroundings. The book also explores the lives of immigrants in the UK, the clash of cultures, and the struggle for identity.

This novel unfolds the heart-wrenching story of a family irrevocably changed one snowy night in 1964. When a doctor is forced to deliver his own twins, he makes a split-second decision to send his newborn daughter, born with Down syndrome, away with the nurse, instructing her to place the baby in an institution. Instead, the nurse moves to another city and raises the girl as her own. The secret of the daughter's existence creates a silent chasm in the doctor's marriage and profoundly affects their son, as the lie that was meant to protect them all slowly erodes their lives. Spanning a quarter of a century, the novel explores themes of love, loss, and the complex nature of family and identity.

"The Position" is a novel that explores the impact of a bestselling sex manual, written by a couple, on their four children. The book, published in the 1970s, includes explicit illustrations of the couple and becomes a cultural phenomenon. The narrative, spanning over three decades, delves into the lives of the children, their struggles with their parents' public sexual revelations, and how it affects their own relationships and identities as they grow into adulthood.