The protagonist, a young stockbroker in New Orleans, is alienated, detached, and finds more reality in movies and books than in his everyday life. He searches for meaning in life, often through his relationships with his aunt and his cousin, while also dealing with existential dread and the impending reality of turning 30. This exploration of alienation and search for identity in the modern world won the National Book Award for Fiction.

This novel is a complex, multi-layered narrative that explores themes of addiction, recovery, and the human condition in a near-future society. The story is set in a tennis academy and a halfway house for recovering addicts, and it intertwines the lives of its numerous characters, including a gifted but troubled teenage tennis prodigy, his filmmaker father, and a group of Quebecois separatists. The book is known for its length, intricate plot, and extensive use of footnotes.

"Wise Blood" is a novel about a young man named Hazel Motes, who returns home to Tennessee after serving in World War II and finds his religious beliefs shaken. He becomes a street preacher, founding the Church Without Christ to preach his message of faithlessness. The book explores themes of redemption, faith, and the struggle between belief and atheism as Hazel interacts with a variety of eccentric characters and faces his own internal battles.

"Correction" is a complex narrative revolving around the life of a man named Roithamer, a genius obsessed with constructing an architectural masterpiece, the Cone, in the center of the Kobernausser forest. The story is told through the perspective of his friend who is reading Roithamer's notes after his suicide. The novel explores themes of obsession, isolation, and the pursuit of perfection, while also delving into the protagonist's troubled relationships with his family and society.

The book is a darkly introspective narrative that delves into the mind of a reclusive, obsessive intellectual who is struggling to complete his scholarly work on the composer Mendelssohn. As he grapples with his own ailments and the perceived mediocrity of his surroundings, the protagonist's stream-of-consciousness monologue reveals his deep-seated anxieties, self-loathing, and profound isolation. The narrative is a relentless examination of the protagonist's psyche, showcasing his critical view of society and his own personal relationships, which are fraught with tension and dysfunction. Through this, the novel explores themes of artistic creation, intellectual elitism, and the suffocating nature of expectations and familial obligations.

Woodcutters is a darkly humorous critique of Vienna's artistic elite. The story takes place over the course of a single evening, as the narrator attends a dinner party in honor of a recently successful actor. As the evening progresses, he reflects on the pretentiousness and hypocrisy of the guests, the mediocrity of their artistic achievements, and the tragic suicide of his former lover. The novel is a scathing indictment of the vanity and self-delusion of the artistic community.

The novel follows a mentally unstable man who begins to experience visions after being hit by a mysterious pink light. Convinced the light is a divine entity named VALIS, he and his friends embark on a quest to understand and communicate with it. As they delve into philosophy, religion, and science, the boundaries between reality and delusion begin to blur, leaving both the characters and the reader questioning the nature of existence.

"Wittgenstein's Nephew" is a semi-autobiographical novel that explores the friendship between the narrator and his friend Paul, who is the nephew of the famous philosopher Ludwig Wittgenstein. The story takes place in Vienna and is set against the backdrop of the Austrian mental health system. The novel delves into themes of sanity, insanity, and the fine line that separates the two, while also offering a critique of Austrian society. It is a meditation on the nature of illness, both physical and mental, and the impact it has on personal relationships and one's perception of the world.

"The Loser" is a philosophical novel that revolves around the complex relationship between three friends who are all piano virtuosos. The narrative is driven by the protagonist's obsession with his friend's suicide, which he believes was triggered by the realization that they could never surpass the genius of their third friend. The book delves into the protagonist's psyche as he grapples with themes of talent, ambition, failure, and the destructive power of comparison.

"Nog" is a surreal and psychedelic tale of a man's journey through a chaotic and disorienting world. The protagonist, Nog, embarks on an existential adventure across America, encountering a series of bizarre characters and situations along the way. The narrative is often nonlinear and disjointed, reflecting Nog's fragmented perception of reality. The book is a critique of the American Dream and explores themes of alienation, disillusionment, and the search for meaning in a seemingly senseless world.

The novel is a darkly humorous exploration of existential themes, following the story of a man who, after a suicide attempt, is rescued by a doctor specializing in "mythotherapy." He embarks on a journey of self-discovery, taking a job at a car dealership in a small town and becoming entangled in a complex love triangle with a fellow teacher and his wife. The narrative delves into the characters' psychological struggles and the absurdity of their attempts to find meaning in life, culminating in a series of bizarre and tragic events that force the protagonist to confront the consequences of his actions and the limitations of his philosophical musings.

In "Something Happened," the narrative delves into the mind of Bob Slocum, a successful yet disillusioned corporate executive navigating the complexities of his personal and professional life in post-war America. The novel, characterized by its stream-of-consciousness style, explores themes of anxiety, isolation, and the mundane horrors of everyday existence as Slocum grapples with his relationships with his family, his colleagues, and himself. Through a series of introspective and often disjointed reflections, the protagonist reveals his deep-seated fears and desires, painting a stark and unsettling portrait of a man overwhelmed by the banalities and moral ambiguities of American middle-class life.