The protagonist, a young stockbroker in New Orleans, is alienated, detached, and finds more reality in movies and books than in his everyday life. He searches for meaning in life, often through his relationships with his aunt and his cousin, while also dealing with existential dread and the impending reality of turning 30. This exploration of alienation and search for identity in the modern world won the National Book Award for Fiction.

This novel is a complex, multi-layered narrative that explores themes of addiction, recovery, and the human condition in a near-future society. The story is set in a tennis academy and a halfway house for recovering addicts, and it intertwines the lives of its numerous characters, including a gifted but troubled teenage tennis prodigy, his filmmaker father, and a group of Quebecois separatists. The book is known for its length, intricate plot, and extensive use of footnotes.

"Wise Blood" is a novel about a young man named Hazel Motes, who returns home to Tennessee after serving in World War II and finds his religious beliefs shaken. He becomes a street preacher, founding the Church Without Christ to preach his message of faithlessness. The book explores themes of redemption, faith, and the struggle between belief and atheism as Hazel interacts with a variety of eccentric characters and faces his own internal battles.

The novel follows a mentally unstable man who begins to experience visions after being hit by a mysterious pink light. Convinced the light is a divine entity named VALIS, he and his friends embark on a quest to understand and communicate with it. As they delve into philosophy, religion, and science, the boundaries between reality and delusion begin to blur, leaving both the characters and the reader questioning the nature of existence.

"Nog" is a surreal and psychedelic tale of a man's journey through a chaotic and disorienting world. The protagonist, Nog, embarks on an existential adventure across America, encountering a series of bizarre characters and situations along the way. The narrative is often nonlinear and disjointed, reflecting Nog's fragmented perception of reality. The book is a critique of the American Dream and explores themes of alienation, disillusionment, and the search for meaning in a seemingly senseless world.

The book is a satirical self-help guide that explores the human condition and our place in the universe through a series of thought experiments, quizzes, and essays. It delves into topics such as existentialism, semiotics, philosophy, science, and religion, all with a humorous twist. The book challenges readers to examine their lives, their beliefs, and their perceptions of reality, ultimately suggesting that we are all a little lost in the cosmos.

The novel is a darkly humorous exploration of existential themes, following the story of a man who, after a suicide attempt, is rescued by a doctor specializing in "mythotherapy." He embarks on a journey of self-discovery, taking a job at a car dealership in a small town and becoming entangled in a complex love triangle with a fellow teacher and his wife. The narrative delves into the characters' psychological struggles and the absurdity of their attempts to find meaning in life, culminating in a series of bizarre and tragic events that force the protagonist to confront the consequences of his actions and the limitations of his philosophical musings.

In "Something Happened," the narrative delves into the mind of Bob Slocum, a successful yet disillusioned corporate executive navigating the complexities of his personal and professional life in post-war America. The novel, characterized by its stream-of-consciousness style, explores themes of anxiety, isolation, and the mundane horrors of everyday existence as Slocum grapples with his relationships with his family, his colleagues, and himself. Through a series of introspective and often disjointed reflections, the protagonist reveals his deep-seated fears and desires, painting a stark and unsettling portrait of a man overwhelmed by the banalities and moral ambiguities of American middle-class life.