Set against the backdrop of the Prague Spring period of Czechoslovak history, the novel explores the philosophical concept of Nietzsche's eternal return through the intertwined lives of four characters: a womanizing surgeon, his intellectual wife, his naïve mistress, and her stoic lover. The narrative delves into their personal struggles with lightness and heaviness, freedom and fate, love and betrayal, and the complexities of human relationships, all while offering a profound meditation on the nature of existence and the paradoxes of life.

The protagonist, a young stockbroker in New Orleans, is alienated, detached, and finds more reality in movies and books than in his everyday life. He searches for meaning in life, often through his relationships with his aunt and his cousin, while also dealing with existential dread and the impending reality of turning 30. This exploration of alienation and search for identity in the modern world won the National Book Award for Fiction.

"Down There" is a novel that follows the life of a Parisian novelist who is disillusioned with his mundane life and seeks solace in the occult. His journey leads him to a satanic priest who introduces him to the dark world of satanism. The protagonist becomes deeply involved in this world, experiencing hallucinations and disturbing visions. The book is a deeply psychological exploration of the human fascination with evil and the macabre, set against the backdrop of late 19th-century Parisian society.

The book is a satirical self-help guide that explores the human condition and our place in the universe through a series of thought experiments, quizzes, and essays. It delves into topics such as existentialism, semiotics, philosophy, science, and religion, all with a humorous twist. The book challenges readers to examine their lives, their beliefs, and their perceptions of reality, ultimately suggesting that we are all a little lost in the cosmos.

"The Denial of Death" is a thought-provoking examination of the influence of death on human behavior and society. The author argues that the fear of death is a primary motivator in human life, influencing our actions, beliefs, and relationships. He explores how culture and religion are often mechanisms to deny and transcend the reality of death, offering symbolic immortality through beliefs in the afterlife or in the enduring impact of one's life work. The book also delves into the psychological impact of this denial and the concept of the "heroic individual" who seeks to leave a lasting legacy.